High Phosphate Induces and Klotho Attenuates Kidney Epithelial Senescence and Fibrosis

Cellular senescence is an irreversible cell growth arrest and is associated with aging and age-related diseases. High plasma phosphate (Pi) and deficiency of Klotho contribute to aging and kidney fibrosis, a pathological feature in the aging kidney and chronic kidney disease. This study examined the...

Cur síos iomlán

Na minha lista:
Sonraí Bibleagrafaíochta
Foilsithe in:Front Pharmacol
Main Authors: Maique, Jenny, Flores, Brianna, Shi, Mingjun, Shepard, Sierra, Zhou, Zhiyong, Yan, Shirely, Moe, Orson W., Hu, Ming Chang
Formáid: Artigo
Teanga:Inglês
Foilsithe: Frontiers Media S.A. 2020
Ábhair:
Pharmacology
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7468469/
https://ncbi.nlm.nih.gov/pubmed/32973510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.01273
Clibeanna: Cuir Clib Leis
Gan Chlibeanna, Bí ar an gcéad duine leis an taifead seo a chlibeáil!

Míreanna Comhchosúla