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Glycochenodeoxycholic acid induces stemness and chemoresistance via the STAT3 signaling pathway in hepatocellular carcinoma cells

The poor prognosis of hepatocellular carcinoma (HCC) is primarily attributed to its high frequency of recurrence and resistance to chemotherapy. Epithelial-to-mesenchymal transition (EMT) and the acquisition of cancer stem cells (CSCs) are the fundamental drivers of chemoresistance in HCC. Glycochen...

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Detalhes bibliográficos
Publicado no:Aging (Albany NY)
Main Authors: Shi, Changying, Yang, Jiamei, Hu, Longmiao, Liao, Boyi, Qiao, Liang, Shen, Weifeng, Xie, Feng, Zhu, Guoqing
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7467378/
https://ncbi.nlm.nih.gov/pubmed/32756004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.103751
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