Maintenance of cancer stemness by miR-196b-5p contributes to chemoresistance of colorectal cancer cells via activating STAT3 signaling pathway

Emerging studies indicated that cancer stem cells represent a subpopulation of cells within the tumor that is responsible for chemotherapeutic resistance. However, the underlying mechanism is still not clarified yet. Here we report that miR-196b-5p is dramatically upregulated in CRC tissues and high...

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Veröffentlicht in:Oncotarget
Hauptverfasser: Ren, Dong, Lin, Bihua, Zhang, Xin, Peng, Yao, Ye, Ziyu, Ma, Yan, Liang, Yangfang, Cao, Longbin, Li, Xiangyong, Li, Ronggang, Sun, Lixia, Liu, Qiongru, Wu, Jinhua, Zhou, Keyuan, Zeng, Jincheng
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2017
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5564809/
https://ncbi.nlm.nih.gov/pubmed/28591704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.17971
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