Crystal structures of SARS-CoV-2 ADP-ribose phosphatase: from the apo form to ligand complexes

Among 15 nonstructural proteins (Nsps), the newly emerging Severe Acute Respiratory Syndrome coronavirus 2 (SARS-CoV-2) encodes a large, multidomain Nsp3. One of its units is the ADP-ribose phosphatase domain (ADRP; also known as the macrodomain, MacroD), which is believed to interfere with the host...

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Vydáno v:IUCrJ
Hlavní autoři: Michalska, Karolina, Kim, Youngchang, Jedrzejczak, Robert, Maltseva, Natalia I., Stols, Lucy, Endres, Michael, Joachimiak, Andrzej
Médium: Artigo
Jazyk:Inglês
Vydáno: International Union of Crystallography 2020
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Research Papers
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7467174/
https://ncbi.nlm.nih.gov/pubmed/32939273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2052252520009653
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