IL15 synergizes with radiotherapy to reprogram the tumor immune contexture through a dendritic cell connection

IL15 is a key cytokine for the activation and survival of anti-tumor effectors CD8(+) T and NK cells. Recently published preclinical studies demonstrate that the therapeutic activity of IL15 requires conventional dendritic cells type 1 (cDC1). Radiotherapy cooperates with IL15 by enhancing cDC1 tumo...

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Detaylı Bibliyografya
Yayımlandı:Oncoimmunology
Asıl Yazarlar: Pilones, Karsten A., Charpentier, Maud, Garcia-Martinez, Elena, Demaria, Sandra
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Taylor & Francis 2020
Konular:
Author's View
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7466855/
https://ncbi.nlm.nih.gov/pubmed/32934886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2020.1790716
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