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IL15 synergizes with radiotherapy to reprogram the tumor immune contexture through a dendritic cell connection
IL15 is a key cytokine for the activation and survival of anti-tumor effectors CD8(+) T and NK cells. Recently published preclinical studies demonstrate that the therapeutic activity of IL15 requires conventional dendritic cells type 1 (cDC1). Radiotherapy cooperates with IL15 by enhancing cDC1 tumo...
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| Pubblicato in: | Oncoimmunology |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Taylor & Francis
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7466855/ https://ncbi.nlm.nih.gov/pubmed/32934886 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2020.1790716 |
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