Targeting Aurora A Kinase (AAK) in Platinum-Resistant High Grade Serous Ovarian Cancer

Aurora A kinase (AAK) involved in G(2)-M transition is functionally involved in centrosome maturation and maintaining an active spindle assembly checkpoint. We tested the hypothesis that in platinum-taxane resistant high grade serous ovarian cancer (HGSOC) inhibition of AAK involved in G(2)-M transi...

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Detalles Bibliográficos
Publicado en:Front Oncol
Main Authors: Ganapathi, Ram N., Norris, Eric J., Sutker, Ashley P., Klotz, Kaitlin E., Ganapathi, Mahrukh K.
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2020
Assuntos:
Oncology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7466726/
https://ncbi.nlm.nih.gov/pubmed/32974133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.01354
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