Clonal lineage of high grade serous ovarian cancer in a patient with neurofibromatosis type 1

Neurofibromatosis type 1 (NF1) is caused by mutations in the NF1 gene encoding neurofibromin, which negatively regulates Ras signaling. NF1 patients have an increased risk of developing early onset breast cancer, however, the association between NF1 and high grade serous ovarian cancer (HGSOC) is un...

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Bibliografiske detaljer
Udgivet i:Gynecol Oncol Rep
Main Authors: Norris, Eric J., Jones, Wendell D., Surleac, Marius D., Petrescu, Andrei J., Destephanis, Darla, Zhang, Qing, Hamadeh, Issam, Kneisl, Jeffrey S., Livasy, Chad A., Ganapathi, Ram N., Tait, David L., Ganapathi, Mahrukh K.
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2018
Fag:
Case Report
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5993517/
https://ncbi.nlm.nih.gov/pubmed/29892687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gore.2018.01.005
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