Clonal lineage of high grade serous ovarian cancer in a patient with neurofibromatosis type 1

Neurofibromatosis type 1 (NF1) is caused by mutations in the NF1 gene encoding neurofibromin, which negatively regulates Ras signaling. NF1 patients have an increased risk of developing early onset breast cancer, however, the association between NF1 and high grade serous ovarian cancer (HGSOC) is un...

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Detalhes bibliográficos
Publicado no:Gynecol Oncol Rep
Main Authors: Norris, Eric J., Jones, Wendell D., Surleac, Marius D., Petrescu, Andrei J., Destephanis, Darla, Zhang, Qing, Hamadeh, Issam, Kneisl, Jeffrey S., Livasy, Chad A., Ganapathi, Ram N., Tait, David L., Ganapathi, Mahrukh K.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2018
Assuntos:
Case Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5993517/
https://ncbi.nlm.nih.gov/pubmed/29892687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gore.2018.01.005
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