PARP1 hinders histone H2B occupancy at the NFATc1 promoter to restrain osteoclast differentiation

Induction of nuclear factor of activated T cells cytoplasmic 1 (NFATc1) by macrophage colony-stimulating factor (M-CSF) and receptor activator of NF-κB ligand (RANKL) is essential for macrophage differentiation into osteoclasts (OCs), but the underlying mechanisms remain unclear. The ability of poly...

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Vydáno v:J Bone Miner Res
Hlavní autoři: Wang, Chun, Xiao, Jianqiu, Nowak, Kathrin, Gunasekera, Kapila, Alippe, Yael, Speckman, Sheree, Yang, Tong, Kress, Dustin, Abu-Amer, Yousef, Hottiger, Michael O., Mbalaviele, Gabriel
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7465553/
https://ncbi.nlm.nih.gov/pubmed/31793068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.3927
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