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Protein Arginine Methyltransferase 5 as a Therapeutic Target for KRAS Mutated Colorectal Cancer

Nearly 45% of colorectal cancer (CRC) patients harbor a mutation in their KRAS gene for which, despite many years of research, there are still no targeted therapies available. Protein Arginine Methyltransferase 5 (PRMT5) is a transcription regulator for multiple cellular processes that is currently...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Shifteh, David, Sapir, Tzuriel, Pahmer, Moshe, Haimowitz, Adam, Goel, Sanjay, Maitra, Radhashree
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7465151/
https://ncbi.nlm.nih.gov/pubmed/32731506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12082091
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