Endogenous Carbon Monoxide Signaling Modulates Mitochondrial Function and Intracellular Glucose Utilization: Impact of the Heme Oxygenase Substrate Hemin

Stress-inducible heme oxygenase-1 (HO-1) catalyzes the oxidative cleavage of heme yielding biliverdin, ferrous iron, and carbon monoxide (CO). Heme oxygenase activity has been attributed to antioxidant defense via the redox cycling system of biliverdin and bilirubin. There is increasing evidence tha...

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Detalhes bibliográficos
Publicado no:Antioxidants (Basel)
Main Authors: Stucki, David, Steinhausen, Julia, Westhoff, Philipp, Krahl, Heide, Brilhaus, Dominik, Massenberg, Annika, Weber, Andreas P. M., Reichert, Andreas S., Brenneisen, Peter, Stahl, Wilhelm
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7465082/
https://ncbi.nlm.nih.gov/pubmed/32717801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antiox9080652
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