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Endogenous Carbon Monoxide Signaling Modulates Mitochondrial Function and Intracellular Glucose Utilization: Impact of the Heme Oxygenase Substrate Hemin

Stress-inducible heme oxygenase-1 (HO-1) catalyzes the oxidative cleavage of heme yielding biliverdin, ferrous iron, and carbon monoxide (CO). Heme oxygenase activity has been attributed to antioxidant defense via the redox cycling system of biliverdin and bilirubin. There is increasing evidence tha...

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Bibliografski detalji
Izdano u:Antioxidants (Basel)
Glavni autori: Stucki, David, Steinhausen, Julia, Westhoff, Philipp, Krahl, Heide, Brilhaus, Dominik, Massenberg, Annika, Weber, Andreas P. M., Reichert, Andreas S., Brenneisen, Peter, Stahl, Wilhelm
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7465082/
https://ncbi.nlm.nih.gov/pubmed/32717801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antiox9080652
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