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Phosphorylation Targets of DNA-PK and Their Role in HIV-1 Replication

The DNA dependent protein kinase (DNA-PK) is a trimeric nuclear complex consisting of a large protein kinase and the Ku heterodimer. The kinase activity of DNA-PK is required for efficient repair of DNA double-strand breaks (DSB) by non-homologous end joining (NHEJ). We also showed that the kinase a...

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Detalhes bibliográficos
Publicado no:Cells
Main Authors: Anisenko, Andrey, Kan, Marina, Shadrina, Olga, Brattseva, Anna, Gottikh, Marina
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7464883/
https://ncbi.nlm.nih.gov/pubmed/32824372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9081907
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