C. elegans Models to Study the Propagation of Prions and Prion-Like Proteins

A hallmark common to many age-related neurodegenerative diseases, such as Alzheimer’s disease (AD), Parkinson’s disease (PD), and amyotrophic lateral sclerosis (ALS), is that patients develop proteinaceous deposits in their central nervous system (CNS). The progressive spreading of these inclusions...

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Bibliographic Details
Published in:Biomolecules
Main Authors: Sandhof, Carl Alexander, Hoppe, Simon Oliver, Tittelmeier, Jessica, Nussbaum-Krammer, Carmen
Format: Artigo
Language:Inglês
Published: MDPI 2020
Subjects:
Review
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7464663/
https://ncbi.nlm.nih.gov/pubmed/32824215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom10081188
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