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Impact of Short-Term Hypoxia on Sirtuins as Regulatory Elements in HUVECs
Background: Sirtuins (SIRT) are NAD(+)-dependent deacetylases that are involved in stress response, antioxidative defense, and longevity via posttranslational modifications. SIRT1 directly activates nitric oxide synthase (NOS). Aging is associated with a reduced sirtuin function and reduction of the...
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| 出版年: | J Clin Med |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
MDPI
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7464651/ https://ncbi.nlm.nih.gov/pubmed/32796661 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcm9082604 |
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