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Alterations of sirtuins in mitochondrial cytochrome c-oxidase deficiency
BACKGROUND: Sirtuins are NAD(+) dependent deacetylases, which regulate mitochondrial energy metabolism as well as cellular response to stress. The NAD/NADH-system plays a crucial role in oxidative phosphorylation linking sirtuins and the mitochondrial respiratory chain. Furthermore, sirtuins are abl...
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| Publicado no: | PLoS One |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5653369/ https://ncbi.nlm.nih.gov/pubmed/29059204 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0186517 |
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