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Adenosine A(2B) receptors induce proliferation, invasion and activation of cAMP response element binding protein (CREB) in trophoblast cells

BACKGROUND: Placental hypoxia is a result of abnormal and shallow trophoblast invasion and involved in the pathophysiology of preeclampsia. Hypoxia increases extracellular adenosine levels and plays an important role in the regulation of angiogenesis, proliferation, vascular tone, endothelial permea...

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Detalhes bibliográficos
Main Authors: Darashchonak, Natallia, Koepsell, Brunhild, Bogdanova, Natalia, von Versen-Höynck, Frauke
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3909477/
https://ncbi.nlm.nih.gov/pubmed/24383849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2393-14-2
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