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Adenosine A(2B) receptors induce proliferation, invasion and activation of cAMP response element binding protein (CREB) in trophoblast cells

BACKGROUND: Placental hypoxia is a result of abnormal and shallow trophoblast invasion and involved in the pathophysiology of preeclampsia. Hypoxia increases extracellular adenosine levels and plays an important role in the regulation of angiogenesis, proliferation, vascular tone, endothelial permea...

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Autors principals: Darashchonak, Natallia, Koepsell, Brunhild, Bogdanova, Natalia, von Versen-Höynck, Frauke
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3909477/
https://ncbi.nlm.nih.gov/pubmed/24383849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2393-14-2
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