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mTOR Inhibition Leads to Src-Mediated EGFR Internalisation and Degradation in Glioma Cells
Epidermal Growth Factor receptor (EGFR) is a tyrosine kinase receptor widely expressed on the surface of numerous cell types, which activates several downstream signalling pathways involved in cell proliferation, migration and survival. EGFR alterations, such as overexpression or mutations, have bee...
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| Publicado no: | Cancers (Basel) |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7464593/ https://ncbi.nlm.nih.gov/pubmed/32823532 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12082266 |
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