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mTOR Inhibition Leads to Src-Mediated EGFR Internalisation and Degradation in Glioma Cells
Epidermal Growth Factor receptor (EGFR) is a tyrosine kinase receptor widely expressed on the surface of numerous cell types, which activates several downstream signalling pathways involved in cell proliferation, migration and survival. EGFR alterations, such as overexpression or mutations, have bee...
Gardado en:
| Publicado en: | Cancers (Basel) |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
MDPI
2020
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7464593/ https://ncbi.nlm.nih.gov/pubmed/32823532 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12082266 |
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