mTOR Inhibition Leads to Src-Mediated EGFR Internalisation and Degradation in Glioma Cells

Epidermal Growth Factor receptor (EGFR) is a tyrosine kinase receptor widely expressed on the surface of numerous cell types, which activates several downstream signalling pathways involved in cell proliferation, migration and survival. EGFR alterations, such as overexpression or mutations, have bee...

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Bibliografische gegevens
Gepubliceerd in:Cancers (Basel)
Hoofdauteurs: Colella, Barbara, Colardo, Mayra, Iannone, Gianna, Contadini, Claudia, Saiz-Ladera, Cristina, Fuoco, Claudia, Barilà, Daniela, Velasco, Guillermo, Segatto, Marco, Di Bartolomeo, Sabrina
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI 2020
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7464593/
https://ncbi.nlm.nih.gov/pubmed/32823532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12082266
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