The Temperature-Dependent Effectiveness of Platinum-Based Drugs Mitomycin-C and 5-FU during Hyperthermic Intraperitoneal Chemotherapy (HIPEC) in Colorectal Cancer Cell Lines

Cytoreductive surgery (CRS) followed by hyperthermic intraperitoneal chemotherapy (HIPEC) is a treatment with curative intent for peritoneal metastasis of colorectal cancer (CRC). Currently, there is no standardized HIPEC protocol: choice of drug, perfusate temperature, and duration of treatment var...

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izdano v:Cells
Main Authors: Helderman, Roxan F.C.P.A., Löke, Daan R., Verhoeff, Jan, Rodermond, Hans M., van Bochove, Gregor G.W., Boon, Menno, van Kesteren, Sanne, Garcia Vallejo, Juan J., Kok, H. Petra, Tanis, Pieter J., Franken, Nicolaas A.P., Crezee, Johannes, Oei, Arlene L.
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2020
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7464333/
https://ncbi.nlm.nih.gov/pubmed/32722384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9081775
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