The Temperature-Dependent Effectiveness of Platinum-Based Drugs Mitomycin-C and 5-FU during Hyperthermic Intraperitoneal Chemotherapy (HIPEC) in Colorectal Cancer Cell Lines

Cytoreductive surgery (CRS) followed by hyperthermic intraperitoneal chemotherapy (HIPEC) is a treatment with curative intent for peritoneal metastasis of colorectal cancer (CRC). Currently, there is no standardized HIPEC protocol: choice of drug, perfusate temperature, and duration of treatment var...

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Veröffentlicht in:Cells
Hauptverfasser: Helderman, Roxan F.C.P.A., Löke, Daan R., Verhoeff, Jan, Rodermond, Hans M., van Bochove, Gregor G.W., Boon, Menno, van Kesteren, Sanne, Garcia Vallejo, Juan J., Kok, H. Petra, Tanis, Pieter J., Franken, Nicolaas A.P., Crezee, Johannes, Oei, Arlene L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7464333/
https://ncbi.nlm.nih.gov/pubmed/32722384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9081775
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