The Temperature-Dependent Effectiveness of Platinum-Based Drugs Mitomycin-C and 5-FU during Hyperthermic Intraperitoneal Chemotherapy (HIPEC) in Colorectal Cancer Cell Lines

Cytoreductive surgery (CRS) followed by hyperthermic intraperitoneal chemotherapy (HIPEC) is a treatment with curative intent for peritoneal metastasis of colorectal cancer (CRC). Currently, there is no standardized HIPEC protocol: choice of drug, perfusate temperature, and duration of treatment var...

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Gepubliceerd in:Cells
Hoofdauteurs: Helderman, Roxan F.C.P.A., Löke, Daan R., Verhoeff, Jan, Rodermond, Hans M., van Bochove, Gregor G.W., Boon, Menno, van Kesteren, Sanne, Garcia Vallejo, Juan J., Kok, H. Petra, Tanis, Pieter J., Franken, Nicolaas A.P., Crezee, Johannes, Oei, Arlene L.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI 2020
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7464333/
https://ncbi.nlm.nih.gov/pubmed/32722384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9081775
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