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The Temperature-Dependent Effectiveness of Platinum-Based Drugs Mitomycin-C and 5-FU during Hyperthermic Intraperitoneal Chemotherapy (HIPEC) in Colorectal Cancer Cell Lines

Cytoreductive surgery (CRS) followed by hyperthermic intraperitoneal chemotherapy (HIPEC) is a treatment with curative intent for peritoneal metastasis of colorectal cancer (CRC). Currently, there is no standardized HIPEC protocol: choice of drug, perfusate temperature, and duration of treatment var...

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Publicat a:Cells
Autors principals: Helderman, Roxan F.C.P.A., Löke, Daan R., Verhoeff, Jan, Rodermond, Hans M., van Bochove, Gregor G.W., Boon, Menno, van Kesteren, Sanne, Garcia Vallejo, Juan J., Kok, H. Petra, Tanis, Pieter J., Franken, Nicolaas A.P., Crezee, Johannes, Oei, Arlene L.
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7464333/
https://ncbi.nlm.nih.gov/pubmed/32722384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9081775
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