Activation of Epidermal Growth Factor Receptor Sensitizes Glioblastoma Cells to Hypoxia-Induced Cell Death

Background: The epidermal growth factor receptor (EGFR) signaling pathway is genetically activated in approximately 50% of glioblastomas (GBs). Its inhibition has been explored clinically but produced disappointing results, potentially due to metabolic effects that protect GB cells against nutrient...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cancers (Basel)
Egile Nagusiak: Luger, Anna-Luisa, Lorenz, Nadja I., Urban, Hans, Divé, Iris, Engel, Anna L., Strassheimer, Florian, Dettmer, Katja, Zeiner, Pia S., Shaid, Shabnam, Struve, Nina, Kriegs, Malte, Hofmann, Ute, Oefner, Peter J., Harter, Patrick N., Steinbach, Joachim P., Ronellenfitsch, Michael W.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: MDPI 2020
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7464192/
https://ncbi.nlm.nih.gov/pubmed/32756332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12082144
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