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Exogenous Flupirtine as Potential Treatment for CLN3 Disease

CLN3 disease is a fatal neurodegenerative disorder affecting children. Hallmarks include brain atrophy, accelerated neuronal apoptosis, and ceramide elevation. Treatment regimens are supportive, highlighting the importance of novel, disease-modifying drugs. Flupirtine and its new allyl carbamate der...

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Detalhes bibliográficos
Publicado no:Cells
Main Authors: Maalouf, Katia, Makoukji, Joelle, Saab, Sara, Makhoul, Nadine J., Carmona, Angelica V., Kinarivala, Nihar, Ghanem, Noël, Trippier, Paul C., Boustany, Rose-Mary
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7464162/
https://ncbi.nlm.nih.gov/pubmed/32796515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9081872
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