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Developmental Comparison of Ceramide in Wild-Type and Cln3(Δex7/8) Mouse Brains and Sera
CLN3 disease is a neurodevelopmental disease leading to early visual failure, motor decline, and death. CLN3 pathogenesis has been linked to dysregulation of ceramide, a key intracellular messenger impacting various biological functions. Ceramide is upregulated in brains of CLN3 patients and activat...
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| Publicado en: | Front Neurol |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Frontiers Media S.A.
2019
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6389635/ https://ncbi.nlm.nih.gov/pubmed/30837943 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fneur.2019.00128 |
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