C3G Is Upregulated in Hepatocarcinoma, Contributing to Tumor Growth and Progression and to HGF/MET Pathway Activation

The complexity of hepatocellular carcinoma (HCC) challenges the identification of disease-relevant signals. C3G, a guanine nucleotide exchange factor for Rap and other Ras proteins, plays a dual role in cancer acting as either a tumor suppressor or promoter depending on tumor type and stage. The pot...

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Enregistré dans:
Détails bibliographiques
Publié dans:Cancers (Basel)
Auteurs principaux: Sequera, Celia, Bragado, Paloma, Manzano, Sara, Arechederra, Maria, Richelme, Sylvie, Gutiérrez-Uzquiza, Alvaro, Sánchez, Aránzazu, Maina, Flavio, Guerrero, Carmen, Porras, Almudena
Format: Artigo
Langue:Inglês
Publié: MDPI 2020
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7463771/
https://ncbi.nlm.nih.gov/pubmed/32823931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12082282
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