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Clock Protein Bmal1 and Nrf2 Cooperatively Control Aging or Oxidative Response and Redox Homeostasis by Regulating Rhythmic Expression of Prdx6

Many disorders of aging, including blinding-diseases, are associated with deficiency of brain and muscle arnt-like protein 1 (Bmal1) and, thereby, dysregulation of antioxidant-defense pathway. However, knowledge is limited regarding the role of Bmal1 regulation of antioxidant-pathway in the eye lens...

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Publicado en:Cells
Main Authors: Chhunchha, Bhavana, Kubo, Eri, Singh, Dhirendra P.
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7463585/
https://ncbi.nlm.nih.gov/pubmed/32784474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9081861
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