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Sulforaphane-Induced Klf9/Prdx6 Axis Acts as a Molecular Switch to Control Redox Signaling and Determines Fate of Cells

Sulforaphane (SFN), an activator of transcription factor Nrf2 (NFE2-related factor), modulates antioxidant defense by Nrf2-mediated regulation of antioxidant genes like Peroxiredoxin 6 (Prdx6) and affects cellular homeostasis. We previously observed that dose levels of SFN are crucial in determining...

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Bibliographic Details
Published in:Cells
Main Authors: Chhunchha, Bhavana, Kubo, Eri, Singh, Dhirendra P.
Format: Artigo
Language:Inglês
Published: MDPI 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6829349/
https://ncbi.nlm.nih.gov/pubmed/31569690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells8101159
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