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iPS-Derived Early Oligodendrocyte Progenitor Cells from SPMS Patients Reveal Deficient In Vitro Cell Migration Stimulation

The most challenging aspect of secondary progressive multiple sclerosis (SPMS) is the lack of efficient regenerative response for remyelination, which is carried out by the endogenous population of adult oligoprogenitor cells (OPCs) after proper activation. OPCs must proliferate and migrate to the l...

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Bibliographic Details
Published in:Cells
Main Authors: Lopez-Caraballo, Lidia, Martorell-Marugan, Jordi, Carmona-Sáez, Pedro, Gonzalez-Munoz, Elena
Format: Artigo
Language:Inglês
Published: MDPI 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7463559/
https://ncbi.nlm.nih.gov/pubmed/32751289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9081803
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