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iPS-Derived Early Oligodendrocyte Progenitor Cells from SPMS Patients Reveal Deficient In Vitro Cell Migration Stimulation

The most challenging aspect of secondary progressive multiple sclerosis (SPMS) is the lack of efficient regenerative response for remyelination, which is carried out by the endogenous population of adult oligoprogenitor cells (OPCs) after proper activation. OPCs must proliferate and migrate to the l...

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Detalhes bibliográficos
Publicado no:Cells
Main Authors: Lopez-Caraballo, Lidia, Martorell-Marugan, Jordi, Carmona-Sáez, Pedro, Gonzalez-Munoz, Elena
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7463559/
https://ncbi.nlm.nih.gov/pubmed/32751289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9081803
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