A carregar...

SUMOylation modulates the LIN28A‐let‐7 signaling pathway in response to cellular stresses in cancer cells

LIN28A is a conserved RNA‐binding protein that inhibits the biogenesis of let‐7 microRNAs, thus promoting cancer progression. However, mechanisms underlying the activation of the LIN28A‐let‐7 signaling pathway remain poorly understood. Here, we show that LIN28A is SUMOylated in vivo and in vitro at...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Mol Oncol
Main Authors: Dou, Jinzhuo, Zhang, Hailong, Chen, Ran, Shu, Zimei, Yuan, Haihua, Zhao, Xian, Wang, Yanli, Huang, Jian, Zhou, Aiwu, Yu, Jianxiu
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7463354/
https://ncbi.nlm.nih.gov/pubmed/32333719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12694
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!