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SUMOylation modulates the LIN28A‐let‐7 signaling pathway in response to cellular stresses in cancer cells
LIN28A is a conserved RNA‐binding protein that inhibits the biogenesis of let‐7 microRNAs, thus promoting cancer progression. However, mechanisms underlying the activation of the LIN28A‐let‐7 signaling pathway remain poorly understood. Here, we show that LIN28A is SUMOylated in vivo and in vitro at...
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| Publicado no: | Mol Oncol |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7463354/ https://ncbi.nlm.nih.gov/pubmed/32333719 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12694 |
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