Novel Interleukin-6 Inducible Gene PDZ-Binding Kinase Promotes Tumor Growth of Multiple Myeloma Cells

Multiple myeloma (MM) remains an intractable hematological malignancy, despite recent advances in anti-MM drugs. Here, we show that role of PDZ binding kinase (PBK) in MM tumor growth. We identified that interleukin-6 (IL-6) readily increases PBK expression. Kaplan–Meier analysis showed that the MM...

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Detalhes bibliográficos
Publicado no:J Interferon Cytokine Res
Main Authors: Ota, Akinobu, Hanamura, Ichiro, Karnan, Sivasundaram, Inaguma, Shingo, Takei, Norio, Lam, Vu Quang, Mizuno, Shohei, Kanasugi, Jo, Wahiduzzaman, Md, Rahman, Md Lutfur, Hyodo, Toshinori, Konishi, Hiroyuki, Tsuzuki, Shinobu, Ikeda, Hiroshi, Takami, Akiyoshi, Hosokawa, Yoshitaka
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc., publishers 2020
Assuntos:
Research Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7462034/
https://ncbi.nlm.nih.gov/pubmed/32721246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/jir.2020.0111
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