Protein Tyrosine Phosphatase Non-Receptor Type 2 Function in Dendritic Cells Is Crucial to Maintain Tissue Tolerance

Protein tyrosine phosphatase non-receptor type 2 (PTPN2) plays a pivotal role in immune homeostasis and has been associated with human autoimmune and chronic inflammatory diseases. Though PTPN2 is well-characterized in lymphocytes, little is known about its function in innate immune cells. Our findi...

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Pubblicato in:Front Immunol
Autori principali: Hering, Larissa, Katkeviciute, Egle, Schwarzfischer, Marlene, Busenhart, Philipp, Gottier, Claudia, Mrdjen, Dunja, Komuczki, Juliana, Wawrzyniak, Marcin, Lang, Silvia, Atrott, Kirstin, Becher, Burkhard, Rogler, Gerhard, Scharl, Michael, Spalinger, Marianne R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2020
Soggetti:
Immunology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7462014/
https://ncbi.nlm.nih.gov/pubmed/32973765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.01856
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