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Thymic Engraftment by in vitro-Derived Progenitor T Cells in Young and Aged Mice

T cells play a critical role in mediating antigen-specific and long-term immunity against viral and bacterial pathogens, and their development relies on the highly specialized thymic microenvironment. T cell immunodeficiency can be acquired in the form of inborn errors, or can result from perturbati...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Front Immunol
Hauptverfasser: Singh, Jastaranpreet, Mohtashami, Mahmood, Anderson, Graham, Zúñiga-Pflücker, Juan Carlos
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7462002/
https://ncbi.nlm.nih.gov/pubmed/32973763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.01850
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