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Differential Roles of IDO1 and IDO2 in T and B Cell Inflammatory Immune Responses
Indoleamine-2,3-dioxygenase (IDO)1 and IDO2 are two closely related tryptophan catabolizing enzymes encoded by linked genes. The IDO pathway is also immunomodulatory, with IDO1 well-characterized as a mediator of tumor immune evasion. Due to its homology with IDO1, IDO2 has been proposed to have a s...
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| Опубликовано в: : | Front Immunol |
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| Главные авторы: | , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Frontiers Media S.A.
2020
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7461966/ https://ncbi.nlm.nih.gov/pubmed/32973768 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.01861 |
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