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Key Players in the Mutant p53 Team: Small Molecules, Gene Editing, Immunotherapy
The transcription factor p53 is a key tumor suppressor that is inactivated in almost all cancers due to either point mutations in the TP53 gene or overexpression of its negative regulators. The p53 protein is known as the “cellular gatekeeper” for its roles in facilitating DNA repair, cell cycle arr...
שמור ב:
| הוצא לאור ב: | Front Oncol |
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| Main Authors: | , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Frontiers Media S.A.
2020
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7461930/ https://ncbi.nlm.nih.gov/pubmed/32974171 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.01460 |
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