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Insight From Animals Resistant to Prion Diseases: Deciphering the Genotype – Morphotype – Phenotype Code for the Prion Protein

Prion diseases are a group of neurodegenerative diseases endemic in humans and several ruminants caused by the misfolding of native prion protein (PrP) into pathological conformations. Experimental work and the mad-cow epidemic of the 1980s exposed a wide spectrum of animal susceptibility to prion d...

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Publicat a:Front Cell Neurosci
Autors principals: Myers, Ryan, Cembran, Alessandro, Fernandez-Funez, Pedro
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7461849/
https://ncbi.nlm.nih.gov/pubmed/33013324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2020.00254
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