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D159 and S167 are protective residues in the prion protein from dog and horse, two prion-resistant animals
Prion diseases are fatal neurodegenerative diseases caused by misfolding of the prion protein (PrP). These conditions affect humans and animals, including endemic forms in sheep and deer. Bovine, rodents, and many zoo mamma ls also developed prion diseases during the “mad-cow” epidemic in the 1980’s...
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| Publicado no: | Neurobiol Dis |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6139044/ https://ncbi.nlm.nih.gov/pubmed/30010001 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2018.07.011 |
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