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D159 and S167 are protective residues in the prion protein from dog and horse, two prion-resistant animals

Prion diseases are fatal neurodegenerative diseases caused by misfolding of the prion protein (PrP). These conditions affect humans and animals, including endemic forms in sheep and deer. Bovine, rodents, and many zoo mamma ls also developed prion diseases during the “mad-cow” epidemic in the 1980’s...

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Bibliografische gegevens
Gepubliceerd in:Neurobiol Dis
Hoofdauteurs: Sanchez-Garcia, Jonatan, Fernandez-Funez, Pedro
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2018
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6139044/
https://ncbi.nlm.nih.gov/pubmed/30010001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2018.07.011
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