Crucial Role of AIM/CD5L in the Development of Glomerular Inflammation in IgA Nephropathy

BACKGROUND: IgA nephropathy (IgAN) begins with aberrant IgA deposition in glomeruli, progresses to IgM/IgG/complement codeposition, and results in chronic inflammation and glomerular damage. However, the mechanism that drives such phlogogenic cascade has been unclear. Recently, apoptosis inhibitor o...

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Vydáno v:J Am Soc Nephrol
Hlavní autoři: Takahata, Akiko, Arai, Satoko, Hiramoto, Emiri, Kitada, Kento, Kato, Rina, Makita, Yuko, Suzuki, Hitoshi, Nakata, Junichiro, Araki, Kimi, Miyazaki, Toru, Suzuki, Yusuke
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Nephrology 2020
Témata:
Basic Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7461693/
https://ncbi.nlm.nih.gov/pubmed/32611589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2019100987
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