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The IgM pentamer is an asymmetric pentagon with an open groove that binds the AIM protein

Soluble immunoglobulin M (IgM) forms a pentamer containing a joining (J) chain polypeptide. While IgM pentamer has various immune functions, it also behaves as a carrier of circulating apoptosis inhibitor of macrophage (AIM; also called CD5L) protein that facilitates repair during different diseases...

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Publicat a:Sci Adv
Autors principals: Hiramoto, Emiri, Tsutsumi, Akihisa, Suzuki, Risa, Matsuoka, Shigeru, Arai, Satoko, Kikkawa, Masahide, Miyazaki, Toru
Format: Artigo
Idioma:Inglês
Publicat: American Association for the Advancement of Science 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6179379/
https://ncbi.nlm.nih.gov/pubmed/30324136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aau1199
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