Enteric Oxalate Secretion Mediated by Slc26a6 Defends against Hyperoxalemia in Murine Models of Chronic Kidney Disease

BACKGROUND: A state of oxalate homeostasis is maintained in patients with healthy kidney function. However, as GFR declines, plasma oxalate (P(ox)) concentrations start to rise. Several groups of researchers have described augmentation of oxalate secretion in the colon in models of CKD, but the oxal...

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Bibliographische Detailangaben
Veröffentlicht in:J Am Soc Nephrol
Hauptverfasser: Neumeier, Laura I., Thomson, Robert B., Reichel, Martin, Eckardt, Kai-Uwe, Aronson, Peter S., Knauf, Felix
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Nephrology 2020
Schlagworte:
Basic Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7461683/
https://ncbi.nlm.nih.gov/pubmed/32660969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2020010105
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