Enteric Oxalate Secretion Mediated by Slc26a6 Defends against Hyperoxalemia in Murine Models of Chronic Kidney Disease

BACKGROUND: A state of oxalate homeostasis is maintained in patients with healthy kidney function. However, as GFR declines, plasma oxalate (P(ox)) concentrations start to rise. Several groups of researchers have described augmentation of oxalate secretion in the colon in models of CKD, but the oxal...

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Bibliografiska uppgifter
I publikationen:J Am Soc Nephrol
Huvudupphovsmän: Neumeier, Laura I., Thomson, Robert B., Reichel, Martin, Eckardt, Kai-Uwe, Aronson, Peter S., Knauf, Felix
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society of Nephrology 2020
Ämnen:
Basic Research
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7461683/
https://ncbi.nlm.nih.gov/pubmed/32660969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2020010105
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