Enteric Oxalate Secretion Mediated by Slc26a6 Defends against Hyperoxalemia in Murine Models of Chronic Kidney Disease

BACKGROUND: A state of oxalate homeostasis is maintained in patients with healthy kidney function. However, as GFR declines, plasma oxalate (P(ox)) concentrations start to rise. Several groups of researchers have described augmentation of oxalate secretion in the colon in models of CKD, but the oxal...

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Detalles Bibliográficos
Publicado en:J Am Soc Nephrol
Main Authors: Neumeier, Laura I., Thomson, Robert B., Reichel, Martin, Eckardt, Kai-Uwe, Aronson, Peter S., Knauf, Felix
Formato: Artigo
Idioma:Inglês
Publicado: American Society of Nephrology 2020
Assuntos:
Basic Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7461683/
https://ncbi.nlm.nih.gov/pubmed/32660969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2020010105
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