IDH2 Deficiency Is Critical in Myogenesis and Fatty Acid Metabolism in Mice Skeletal Muscle

Mitochondrial NADP(+)-dependent isocitrate dehydrogenase (IDH2) catalyzes the oxidative decarboxylation of isocitrate into α-ketoglutarate with concurrent reduction of NADP(+) to NADPH. However, it is not fully understood how IDH2 is intertwined with muscle development and fatty acid metabolism. Her...

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Bibliografiske detaljer
Udgivet i:Int J Mol Sci
Main Authors: Pan, Jeong Hoon, Tang, Jingsi, Kim, Young Jun, Lee, Jin Hyup, Shin, Eui-Cheol, Zhao, Jiangchao, Kim, Kee-Hong, Hwang, Kyung A., Huang, Yan, Kim, Jae Kyeom
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
Fag:
Communication
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7460611/
https://ncbi.nlm.nih.gov/pubmed/32764267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21165596
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