Hepatic Transcriptomics Reveals that Lipogenesis Is a Key Signaling Pathway in Isocitrate Dehydrogenase 2 Deficient Mice

Mitochondrial nicotinamide adenine dinucleotide phosphate (NADP(+))-dependent isocitrate dehydrogenase (IDH2) plays a key role in the intermediary metabolism and energy production via catalysing oxidative decarboxylation of isocitrate to α-ketoglutarate in the tricarboxylic acid (TCA) cycle. Despite...

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Publicado en:Genes (Basel)
Autores principales: Pan, Jeong Hoon, Tang, Jingsi, Redding, Mersady C., Beane, Kaleigh E., Conner, Cara L., Cho, Yun Jeong, Zhao, Jiangchao, Kim, Jun Ho, Kong, Byungwhi C., Lee, Jin Hyup, Kim, Jae Kyeom
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2019
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6770969/
https://ncbi.nlm.nih.gov/pubmed/31546946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes10090728
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