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IDH2 Deficiency Aggravates Fructose-Induced NAFLD by Modulating Hepatic Fatty Acid Metabolism and Activating Inflammatory Signaling in Female Mice

Fructose is a strong risk factor for non-alcoholic fatty liver disease (NAFLD), resulting from the disruption of redox systems by excessive reactive oxygen species production in the liver cells. Of note, recent epidemiological studies indicated that women are more prone to developing metabolic syndr...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Nutrients
Hauptverfasser: Pan, Jeong Hoon, Kim, Hoe-Sung, Beane, Kaleigh Elizabeth, Montalbano, Allison Michelle, Lee, Jin Hyup, Kim, Young Jun, Kim, Jun Ho, Kong, Byungwhi Caleb, Kim, Sangyub, Park, Jeen-Woo, Shin, Eui-Cheol, Kim, Jae Kyeom
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6024877/
https://ncbi.nlm.nih.gov/pubmed/29861476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/nu10060679
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