Hepatic Transcriptomics Reveals that Lipogenesis Is a Key Signaling Pathway in Isocitrate Dehydrogenase 2 Deficient Mice

Mitochondrial nicotinamide adenine dinucleotide phosphate (NADP(+))-dependent isocitrate dehydrogenase (IDH2) plays a key role in the intermediary metabolism and energy production via catalysing oxidative decarboxylation of isocitrate to α-ketoglutarate in the tricarboxylic acid (TCA) cycle. Despite...

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Detalhes bibliográficos
Publicado no:Genes (Basel)
Main Authors: Pan, Jeong Hoon, Tang, Jingsi, Redding, Mersady C., Beane, Kaleigh E., Conner, Cara L., Cho, Yun Jeong, Zhao, Jiangchao, Kim, Jun Ho, Kong, Byungwhi C., Lee, Jin Hyup, Kim, Jae Kyeom
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6770969/
https://ncbi.nlm.nih.gov/pubmed/31546946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes10090728
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