Llwytho...

Reverse TCA cycle flux through isocitrate dehydrogenases 1 and 2 is required for lipogenesis in hypoxic melanoma cells

The TCA cycle is the central hub of oxidative metabolism, running in the classic forward direction to provide carbon for biosynthesis and reducing agents for generation of ATP. Our metabolic tracer studies in melanoma cells showed that in hypoxic conditions the TCA cycle is largely disconnected from...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Filipp, Fabian V., Scott, David A., Ronai, Ze’ev A., Osterman, Andrei L., Smith, Jeffrey W.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2012
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3329592/
https://ncbi.nlm.nih.gov/pubmed/22360810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1755-148X.2012.00989.x
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